Carver College of Medicine Events
Women In Micro & Immuno Coffee Hour
Monday, July 14, 2025 11:00am to 12:00pm
Join us for the Women in Micro & Immuno Coffee Hour. It is the monthly coffee hour on the second Monday of the month from 11 a.m. to noon in 1289 CBRB. Enjoy coffee, pastries and contribute to the discussion!This is open to ALL — students, staff, postdocs, and faculty interested in promoting women in science.Speakers change monthly. Contact: jessica-tucker@uiowa.edu for details.
Topics in Human Genetics
Monday, July 14, 2025 12:00pm to 1:00pm
The course is open to individuals wishing to learn more about current topics in Human Genetics who meet the following criteria; individuals must have completed a course in genetics and are currently in a genetics lab, or have past genetics research experience. Genetics educators are also welcome to attend the course.The objective of the course is to provide persons familiar with genetics a broad overview of gene identification, molecular genetics, complex disease, next generation sequencing...
REDCap Advanced Training
Tuesday, July 15, 2025 10:00am to 11:00am
This is the fourth step in the REDCap training series. In this training we will cover advanced features such as:
Importing data from a CSV file
Ways to customize your data entry experience with form display logic
Making your forms more dynamic and personalized with context aware smart variables
Sending automated, conditional email alerts
Ensuring data is high quality by executing data quality rules, creating data 'missingness' codes, and opening data queries
Register by clicking the...
Hardin Open Workshops - PubMed (Zoom)
Wednesday, July 16, 2025 10:00am to 11:00am
This hands-on session will help you improve your searching through best practices for basic and advanced searching and show you features for saving or exporting citations. The session will also help you understand medical subject headings (MeSH) and how they improve your search as well as the benefits of a MyNCBI account.PLEASE NOTE:Class will be taught via Zoom. Advance registration is required. Registrants will be emailed the Zoom link 30 minutes before the class time.
REDCap MyCap Training
Wednesday, July 16, 2025 10:00am to 11:00am
This is the fifth step in the REDCap training series. In this training, we will discuss using the MyCap mobile app for data collection. We will cover features such as:
Creating participants
Creating tasks and schedules
Active tasks and their unique data output
Direct messages and announcements
This training is a demo and not hands-on. After this training, you will have a basic understanding of the MyCap mobile app for REDCap.
Register by clicking the virtual event link above or by going...
Recent Articles from the University of Iowa
Targeting CXCR4 with 212Pb/203Pb-Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer
Thursday, July 3, 2025
Small cell lung cancer (SCLC) has a 6% 5-year overall survival rate. C-X-C chemokine receptor 4 (CXCR4) is an attractive target for theranostic agents, is highly expressed in SCLCs, and can be targeted with pentixather using the theranostic pair 212Pb/203Pb. The hypothesis that 212Pb/203Pb-pentixather can be used safely and effectively for imaging and therapy in SCLC in xenograft models was tested. SPECT-CT imaging and biodistribution studies of tumor-bearing mice injected with 203Pb-pentixather...
Vibrio cholerae endemic to the lower Rio Grande Delta segregate into urban and rural phylotypes
Wednesday, July 2, 2025
The lifestyle of Vibrio cholerae is primarily environmental, yet a chance encounter with a human host can lead to cholera, a potentially lethal form of diarrhea. Strains belonging to O1 and O139 serogroups have pandemic potential, but the contribution of non-O1/non-O139 serovars towards the genesis of cholera remains unclear. Endemic V. cholerae lineages were investigated given several historical accounts describing cholera epidemics and sporadic, contemporary cholera-like outbreaks along the...
A Versatile Reporter Platform for Evaluating HDR- and NHEJ-Based Genome Editing in Airway Epithelial Cell Cultures Using an rAAV Vector
Friday, June 27, 2025
Therapeutic gene editing strategies utilize endogenous DNA repair pathways-nonhomologous end joining (NHEJ) or homology-directed repair (HDR)-to introduce targeted genomic modifications. Because HDR is restricted to dividing cells, whereas NHEJ functions in both dividing and non-dividing cells, NHEJ-based approaches are better suited for in vivo gene editing in the largely post-mitotic airway epithelium. Homology-independent targeted insertion (HITI), an NHEJ-based method, offers a promising...
Detection of Varicella Zoster Virus Reactivation in Cerebrospinal Fluid in Ischemic Stroke or Transient Ischemic Attack
Wednesday, June 18, 2025
CONCLUSIONS: Among individuals who underwent VZV testing in CSF, VZV reactivation was present in 1 of 5 patients with AIS/transient ischemic attack. Patients with HIV were at particularly high risk of VZV reactivation and recurrent ischemic stroke.
Skin levels of toxic shock syndrome toxin-1 predict the severity of atopic dermatitis
Tuesday, June 17, 2025
No abstract
Maternal α-cypermethrin and permethrin exert differential effects on fetal growth, placental morphology, and fetal neurodevelopment in mice
Sunday, June 15, 2025
Pyrethroid insecticides represent a broad class of chemicals used widely in agriculture and household applications. Human studies show mixed effects of maternal pyrethroid exposure on fetal growth and neurodevelopment. Assessment of shared pyrethroid metabolites as a biomarker for exposure obscures effects of specific chemicals within this broader class. To better characterize pyrethroid effects on fetal development, we investigated maternal exposure to permethrin, a type I pyrethroid, and...
Do active learning techniques promote higher academic performance in an online graduate anatomy course?
Saturday, June 14, 2025
Human anatomy is a foundational course in graduate health professional programs. Given the increased enrollment in anatomy courses, along with the development of new technologies, institutions are increasingly compelled to provide alternative course formats, including online learning. Similarly, higher education is increasingly transitioning from traditional lecture-based learning to methods that allow students to actively participate in their own learning process (i.e., active learning). Active...
Airway basal stem cells are necessary for the maintenance of functional intraepithelial airway macrophages
Friday, June 13, 2025
Stem cells are known to provide signals that contribute to the maintenance and function of neighboring cells. We demonstrate that Notch signaling arising from airway basal stem cells is necessary for the function of a unique population of intraepithelial airway macrophages (IAMs) in the murine trachea. Without this stem cell signaling, IAMs lose MHC II expression, which in turn prevents antigen-induced allergic inflammation. Distal murine airways do not harbor basal stem cells, and, in this...
Physiological microbial exposure normalizes memory T cell surveillance of the brain and modifies host seizure outcomes
Friday, June 13, 2025
Recent studies have highlighted the presence of memory T cells in human brains, some of which are specific for peripheral infections. To address their potential origins, we used two models of polymicrobial exposure to 'normalize' the immune systems of specific pathogen-free mice and queried the impact on brain T cell biology. Here, we show that cohousing and sequential infection induce marked enhancement of memory T cells in the brain tissue of mice. These resident and circulating memory T cells...
Inhibition of Influenza Entry by Organosilicon Compounds
Tuesday, June 10, 2025
Hemagglutinin (HA) plays a critical role in the entry of influenza and thus HA is a target for the development of entry inhibitors as antivirals. One of the first small molecule inhibitors of influenza entry to be described was tert-butylhydroquinone (TBHQ), a commonly used antioxidant. This compound was shown to inhibit influenza containing Group 2 HA, such as H3 and H7 HA circulating in humans and avians. One limitation of TBHQ is the propensity to oxidize in solution, resulting in a less...