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Carver College of Medicine Events

Mobile Clinic- DVIP Center

Sunday, July 5, 2026 1:30pm to 3:30pm
TBD
Student run free medical clinic

REDCap Basic Training

Tuesday, July 7, 2026 10:00am to 11:30am
Virtual

This is the first step in the REDCap training series. In this training, we will build a new REDCap project from scratch and cover basic features such as:

• Building forms with proper field types and validation
• Assigning user permissions
• Project backup and overview with data dictionary, codebook, pdf, and xml
• Ensuring your project works properly by testing with real world application
• Making mid-study modifications safely after having started data collection in production
• Creating and...

Neuroscience Interdisciplinary Program Thesis Defense Seminar: Ahmet Kuralay promotional image

Neuroscience Interdisciplinary Program Thesis Defense Seminar: Ahmet Kuralay

Tuesday, July 7, 2026 2:00pm
Medical Education Research Facility

Ahmet Kuralay is a PhD candidate in the Neuroscience Interdisciplinary Graduate Program. His research has been conducted in Dr. Jon Resch's laboratories.

If you are unable to attend in person, please consider showing your support and attending via Zoom. Please email britt-hokanson@uiowa.edu for the zoom link.

REDCap Intermediate Training

Wednesday, July 8, 2026 10:00am to 11:00am
Virtual

This is the second step in the REDCap training series. In this training we will cover basic and intermediate features such as:
• Outputting data automatically with calculated fields
• Collecting the same data points multiple times with longitudinal and one-to-many data collection
• Standardizing your data to industry standards with ontologies and the REDCap Instrument Library
• Ways to customize your data entry experience with action tags
• Viewing data with reports, dashboards, and charts
• And more

T...

REDCap Surveys Training

Thursday, July 9, 2026 10:00am to 11:00am
Virtual

This is the third step in the REDCap training series. In this training, we will cover survey configuration and distribution such as:

Allowing potential participants to self-initiate participation in your study with public surveys

Manually and automatically sending surveys

Administering electronic consent (e-consent) forms

Controlling survey access with conditional logic and survey login

This training is a demo and not hands-on. After this training you will have a basic understanding of surveys in...

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Recent Articles from the University of Iowa

Break-induced replication forms long mutable single-strand DNA during meiosis

Saturday, June 20, 2026
Jerzy M Twarowski
In meiosis, homologous recombination (HR) facilitates the halving of genomic content in diploid parents to produce haploid gametes, while also reshuffling genetic material. However, studies in yeast and mammals have suggested that HR during meiosis also makes the process mutagenic, and it has been proposed that the single-strand (ss) DNA formed by HR of programmed double-strand breaks (DSBs) contributes to the observed mutagenesis. To determine the full mutagenic potential of ssDNA formed during...

MMP9 Genotype and Systemic T-Cell Subsets Correlate With Structural and Functional Outcomes in Neovascular Age-Related Macular Degeneration

Tuesday, June 16, 2026
Thomas L Martinez
CONCLUSIONS: MMP9 genotype affects structural and functional outcomes in patients with nvAMD. Along with the observed systemic immune dysregulation, these findings support the role of a MMP9-dendritic-T-cell axis in nvAMD immunopathogenesis and highlight this as a potential therapeutic target.

Antibacterial activity of glycerol monolaurate formulated in petrolatum

Tuesday, June 16, 2026
Patrick M Schlievert
Glycerol monolaurate (GML) is a fatty acid monoester of glycerol that is approved by the FDA as a food additive and component of cosmetics. We previously showed that 50,000 µg/mL of GML solubilized in the non-aqueous K-Y Warming Gel is broadly antibacterial, including S. aureus and various streptococcal species, and selectively increases beneficial lactobacilli. GML is also anti-inflammatory, reducing harmful inflammation. In the current study, we examined GML and longer or shorter fatty acid...

The Impact of Kidney Donor Profile Index and Human Leukocyte Antigen Mismatch on Graft Survival in Pediatric Kidney Transplant Recipients

Wednesday, June 10, 2026
Saritha Ranabothu
CONCLUSION: HLA mismatch is a stronger predictor of graft outcomes than KDPI in pediatric kidney transplantation. The limited number of high-KDPI donors in pediatric recipients may explain the lack of significant association with KDPI. These findings support efforts to minimize HLA mismatches in pediatric allocation strategies.

Engineered tRNA reduces vision loss in a mouse model of Leber congenital amaurosis

Tuesday, June 9, 2026
Pawan K Shahi
Premature termination codons (PTCs) are a major class of pathogenic variants that underlie rare inherited disorders, including forms of childhood blindness. Therapeutic suppression of these "nonsense mutations" offers a gene- and position-agnostic strategy to restore protein function. Our previous work established that the W53X PTC in the KCNJ13 gene causes Leber congenital amaurosis type 16 (LCA16) by disrupting the inwardly rectifying potassium channel Kir7.1, leading to retinal pigment...

Inhibition of histone demethylase LSD1 suppresses CD47 expression and enhances efficacy of CD47 blockade in breast cancer

Thursday, June 4, 2026
Fengjie Jiang
CONCLUSION: Targeting LSD1 enhances the efficacy of anti-CD47 therapy by overcoming immune evasion, offering a promising strategy to improve immunotherapy outcomes in TNBC.

Human germline biallelic loss-of-function OSMR variants cause severe allergic disease

Monday, June 1, 2026
Simran Samra
Oncostatin M (OSM) receptor beta (OSMRβ), encoded by OSMR, is a cytokine receptor subunit required for signaling by OSM and IL-31. We identified 10 affected individuals from seven unrelated families with germline biallelic loss-of-function variants in OSMR who shared a phenotype of early-onset, severe, widespread atopic dermatitis with peripheral eosinophilia and markedly elevated serum IgE. All patient-derived OSMRβ variants failed to localize to the cell surface, resulting in selective loss of...

Decoding Immune Mechanisms in BCG-unresponsive Non-muscle Invasive Bladder Cancer

Saturday, May 30, 2026
Mohamad Abou Chakra
Non-muscle-invasive bladder cancer (NMIBC) accounts for roughly 75% of all bladder cancer cases. For patients with intermediate- and high-risk disease, intravesical Bacillus Calmette-Guérin (BCG) remains the standard treatment, yet it fails in up to 40% of cases. While radical cystectomy is the most effective salvage option, it carries significant morbidity and long-term quality-of-life consequences, highlighting the urgent need for bladder-sparing alternatives. Advancing such therapies requires...

Pharmacological METTL3 inhibition attenuates HIV-1 latency reversal in CD4<sup>+</sup> T cells

Friday, May 29, 2026
Tarun Mishra
N⁶-methyladenosine (m⁶A) is a major epitranscriptomic modification that regulates RNA metabolism and affects the replication and latency reversal of human immunodeficiency virus type 1 (HIV-1) in cells. Methyltransferase-like 3 (METTL3) is the principal catalytic enzyme responsible for m⁶A deposition, and its pharmacological inhibition has emerged as a potential therapeutic strategy for cancer and viral infections. However, the relative potency of METTL3 inhibitors in reducing m⁶A levels and...

Neocortical tau burden determines the degree of cognitive impairment in individuals with Braak stage V neurofibrillary degeneration

Monday, May 25, 2026
Timothy E Richardson
Alzheimer disease neuropathologic change (ADNC) is considered to be the most common cause of cognitive decline and dementia worldwide. ADNC level is determined using the density of neuritic plaques in combination with the topographical distribution of β-amyloid (Aβ) plaques and hyperphosphorylated tau (p-tau)-positive neurofibrillary tangles (NFTs). While cognitive decline correlates with the level of ADNC, there remains a great deal of variation in cognitive outcomes between individuals that is...