Carver College of Medicine Events
REDCap MyCap Training
Wednesday, June 10, 2026 10:00am to 11:00am
This is the fifth step in the REDCap training series. In this training, we will discuss using the MyCap mobile app for data collection. We will cover features such as:
Creating participants
Creating tasks and schedules
Active tasks and their unique data output
Direct messages and announcements
This training is a demo and not hands-on. After this training, you will have a basic understanding of the MyCap mobile app for REDCap.
Register by clicking the virtual event link above or by going here: https:/...
Hardin Open Workshops - PubMed (Zoom)
Wednesday, June 10, 2026 1:00pm to 2:00pm
This hands-on session will help you improve your searching through best practices for basic and advanced searching and show you features for saving or exporting citations. The session will also help you understand medical subject headings (MeSH) and how they improve your search as well as the benefits of a MyNCBI account.
PLEASE NOTE:
Enrollment in HOW is open to all University of Iowa affiliates and residents of the state of Iowa. Advance registration is required for Zoom classes, though walk-ins...
REDCap Data Handling
Thursday, June 11, 2026 10:00am to 11:00am
This is the sixth and final step in the REDCap training series. In this training we won't use REDCap at all. Instead, we will cover ways to view and manage your exported REDCap data in Microsoft Excel and Sublime Text such as:
Populating data from one Excel sheet to another with vlookup()
Seeing specific data with column sorting and filtering
Ensuring data is cohesive by creating tables
Looking at how data relates to other data by creating pivot tables
Transforming unusable data to a usable format...
Biomedical & Health Informatics Community Meeting
Thursday, June 11, 2026 12:00pm to 1:00pm
We have established a community of CCOM Informaticists who are applying these skills in their work at UIHC. You are invited to join us during our monthly seminar presentations.
Biomedical & Health Informatics Community Meeting
Thursday, June 11, 2026 12:00pm to 1:00pm
Biomedical and Health Informatics Community Meeting June 11, 2026
Recent Articles from the University of Iowa
Human germline biallelic loss-of-function OSMR variants cause severe allergic disease
Monday, June 1, 2026
Oncostatin M (OSM) receptor beta (OSMRβ), encoded by OSMR, is a cytokine receptor subunit required for signaling by OSM and IL-31. We identified 10 affected individuals from seven unrelated families with germline biallelic loss-of-function variants in OSMR who shared a phenotype of early-onset, severe, widespread atopic dermatitis with peripheral eosinophilia and markedly elevated serum IgE. All patient-derived OSMRβ variants failed to localize to the cell surface, resulting in selective loss of...
Decoding Immune Mechanisms in BCG-unresponsive Non-muscle Invasive Bladder Cancer
Saturday, May 30, 2026
Non-muscle-invasive bladder cancer (NMIBC) accounts for roughly 75% of all bladder cancer cases. For patients with intermediate- and high-risk disease, intravesical Bacillus Calmette-Guérin (BCG) remains the standard treatment, yet it fails in up to 40% of cases. While radical cystectomy is the most effective salvage option, it carries significant morbidity and long-term quality-of-life consequences, highlighting the urgent need for bladder-sparing alternatives. Advancing such therapies requires...
Pharmacological METTL3 inhibition attenuates HIV-1 latency reversal in CD4<sup>+</sup> T cells
Friday, May 29, 2026
N⁶-methyladenosine (m⁶A) is a major epitranscriptomic modification that regulates RNA metabolism and affects the replication and latency reversal of human immunodeficiency virus type 1 (HIV-1) in cells. Methyltransferase-like 3 (METTL3) is the principal catalytic enzyme responsible for m⁶A deposition, and its pharmacological inhibition has emerged as a potential therapeutic strategy for cancer and viral infections. However, the relative potency of METTL3 inhibitors in reducing m⁶A levels and...
Neocortical tau burden determines the degree of cognitive impairment in individuals with Braak stage V neurofibrillary degeneration
Monday, May 25, 2026
Alzheimer disease neuropathologic change (ADNC) is considered to be the most common cause of cognitive decline and dementia worldwide. ADNC level is determined using the density of neuritic plaques in combination with the topographical distribution of β-amyloid (Aβ) plaques and hyperphosphorylated tau (p-tau)-positive neurofibrillary tangles (NFTs). While cognitive decline correlates with the level of ADNC, there remains a great deal of variation in cognitive outcomes between individuals that is...
Updated trends in the global prevalence and burden of mental disorders, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023
Thursday, May 21, 2026
BACKGROUND: The 2023 iteration of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) estimated prevalence, incidence, and health burden for 375 diseases and injuries, including 12 mental disorders. We assess past, current, and emerging trends in the prevalence and burden of mental disorders across sexes and age groups, for 21 regions, 204 countries and territories, and by Socio-demographic Index (SDI) quintile, from 1990 to 2023.
The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney
Tuesday, May 12, 2026
Due to aging, the efficiency of kidney function begins to decrease. Dysfunction in mitochondria and their cristae is a hallmark of aging. Therefore, age-related decline in kidney function could be attributed to changes in mitochondrial ultrastructure, increased reactive oxygen species, and alterations in metabolism and lipid composition. We sought to understand how mitochondrial ultrastructure is altered over time in tubular kidney cells. A serial block face-scanning electron microscope and...
Establishment of pediatric reference ranges for circulating naive and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience
Tuesday, May 12, 2026
Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice. Notable examples of these advances include successfully harnessing the therapeutic potential of the immune system (immunotherapy), as well as an expanding menu...
Circulating natural killer cells are phenotypically and functionally altered in age-related macular degeneration
Friday, May 8, 2026
Age-related macular degeneration (AMD) is the leading cause of irreversible central blindness and can result in pathological neovascularization. Using a "human-first" approach, we identify immunotherapy as a disease modifier in models of neovascular AMD (nAMD). Plasma cytokine analysis in a large population cohort reveals an imbalance of lymphocytic cytokines associated with severity of AMD, leading to discovery of a skewed peripheral natural killer (NK) cell phenotype in individuals with AMD....
Respiratory infections due to human common cold coronaviruses, SARS-CoV, MERS-CoV, and SARS-CoV-2: epidemiology, pathogenesis, clinical features, diagnostics, therapeutics, and vaccine landscapes
Thursday, May 7, 2026
Over the past half-century, perceptions of human coronaviruses have evolved from their initial characterisation as causes of the common cold to recognition of their capacity to trigger severe disease and global epidemics. The emergence of three zoonotic coronaviruses-severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002, Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, and SARS-CoV-2 in 2019, has had profound health, economic, and societal consequences and continues to...
Presynaptic Ca<sub>V</sub>2.1 calcium dependent facilitation is essential for faithful auditory information transfer
Monday, May 4, 2026
Activity-dependent modulation of presynaptic voltage-gated Ca^(2+) channels (Ca(V)2) regulates Ca^(2+) influx to control neuronal circuit output. Although Ca(V)2.1 can undergo robust Ca^(2+) dependent facilitation (CDF), whether it occurs in native central nervous system neuronal circuits is disputed. Accurate auditory information processing requires precise and reliable synaptic transmission at high activity rates in the auditory brainstem. To determine if Ca(V)2.1 CDF is a key regulator of...