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Skills for Educators: Interactive Lecturing

Friday, September 22, 2023 8:30am to 11:30am
University of Iowa Hospitals and Clinics
Deliver effective, interactive presentations. • Describe components of effective presentations • Apply specific techniques for making presentations more interactive and memorable
Three Minute Thesis: Research On Stage promotional image

Three Minute Thesis: Research On Stage

Friday, September 22, 2023 1:30pm to 3:00pm
Seamans Center
Learn theatrical techniques (breath, movement, and body language) to help improve presentation skills, including how to find a hook to get audiences interested in your research, how to feel more comfortable speaking in front of groups and how to create engaging oral presentations. 

Annual University of Iowa Deeded Body Memorial Service

Friday, September 22, 2023 1:30pm to 2:30pm
Oakland Cemetery
The Annual University of Iowa Deeded Body Memorial Service recognizes and honors individuals who donated their bodies to advancing medical science over the last year.
BMindful Holy Days: Yom Kippur (Judaism) promotional image

BMindful Holy Days: Yom Kippur (Judaism)

Sunday, September 24 7:00pm to Monday, September 25, 2023 6:59pm
University of Iowa Division of Diversity, Equity, and Inclusion
BMindful is an initiative that seeks to meet the needs of diverse communities by providing event and conference planners with the dates of holy days of major religious faiths for five years into the future. By providing these dates in advance, BMindful seeks to help planners avoid those dates when scheduling events. BMindful does not include all religious holy days. It focuses on three major holy days for each faith—days when faith members may choose not to go to work or send their children to...
Hardin Open Workshops - Systematic Reviews, Part 1: Nuts & Bolts (In-Person & Zoom) promotional image

Hardin Open Workshops - Systematic Reviews, Part 1: Nuts & Bolts (In-Person & Zoom)

Monday, September 25, 2023 12:00pm to 1:00pm
Hardin Library for Health Sciences
This class will provide a framework for developing a literature search for a systematic review. Topics will include the following: standards and criteria to consider, establishing a plan, registering a protocol, developing a research question, determining where to search, identifying search terms, reporting search strategies, and managing references. PLEASE NOTE Advance registration is required for Zoom classes, though walk-ins are welcome for in-person classes. Virtual registrants will be...
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Recent Articles from the University of Iowa

IL-13 induced inflammation increases DPP4 abundance but does not enhance MERS-CoV replication in airway epithelia

Tuesday, September 12, 2023
Kun Li
CONCLUSIONS: Our results suggest that increased DPP4 abundance is likely not the primary mechanism leading to increased MERS severity in the setting of Th2 inflammation. Transcriptional profiling analysis highlighted the complexity of IL-13 induced changes in airway epithelia, including altered expression of genes involved in innate immunity, antiviral responses, and maintenance of the extracellular mucus barrier. These data suggest that additional factors likely interact with DPP4 abundance to...

SARS-CoV-2 infection of polarized human airway epithelium induces necroptosis that causes airway epithelial barrier dysfunction

Wednesday, September 6, 2023
Siyuan Hao
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause the ongoing pandemic of coronavirus disease 2019 (COVID19). One key feature associated with COVID-19 is excessive pro-inflammatory cytokine production that leads to severe acute respiratory distress syndrome. Although the cytokine storm induces inflammatory cell death in the host, which type of programmed cell death mechanism that occurs in various organs and cells remains elusive. Using an in vitro culture model of...

Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial

Monday, August 28, 2023
Angela R Branche
Vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection wanes over time, requiring updated boosters. In a phase 2, open-label, randomized clinical trial with sequentially enrolled stages at 22 US sites, we assessed safety and immunogenicity of a second boost with monovalent or bivalent variant vaccines from mRNA and protein-based platforms targeting wild-type, Beta, Delta and Omicron BA.1 spike antigens. The primary outcome was pseudovirus neutralization...

Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure

Wednesday, August 23, 2023
Amanda Bullert
The disposition and toxicity of lower chlorinated PCBs (LC-PCBs) with less than five chlorine substituents have received little attention. This study characterizes the distribution and metabolomic effects of PCB 52, an LC-PCB found in indoor and outdoor air, three weeks after intraperitoneal exposure of female Sprague Dawley rats to 0, 1, 10, or 100 mg/kg BW. PCB 52 exposure did not affect overall body weight. Gas chromatography-tandem mass spectrometry (GC-MS/MS) analysis identified PCB 52 in...

The Calm after the Storm: Implications of Sepsis Immunoparalysis on Host Immunity

Monday, August 21, 2023
Elvia E Silva
The immunological hallmarks of sepsis include the inflammation-mediated cytokine storm, apoptosis-driven lymphopenia, and prolonged immunoparalysis. Although early clinical efforts were focused on increasing the survival of patients through the first phase, studies are now shifting attention to the long-term effects of sepsis on immune fitness in survivors. In particular, the most pertinent task is deciphering how the immune system becomes suppressed, leading to increased incidence of secondary...

Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury

Friday, August 18, 2023
Brittany P Todd
Accumulating evidence suggests that type I interferon (IFN-I) signaling is a key contributor to immune cell-mediated neuropathology in neurodegenerative diseases. Recently, we demonstrated a robust upregulation of type I interferon-stimulated genes in microglia and astrocytes following experimental traumatic brain injury (TBI). The specific molecular and cellular mechanisms by which IFN-I signaling impacts the neuroimmune response and neuropathology following TBI remains unknown. Using the...

Efferocytosis of viable versus heat-inactivated MSC induces human monocytes to distinct immunosuppressive phenotypes

Thursday, August 17, 2023
Michael V Schrodt
CONCLUSION: Collectively, these studies show that the quality of MSCs efferocytosed by monocytes polarize monocytes toward distinctive immunosuppressive phenotypes and highlights the need to tailor MSC therapies for specific indications.

Infants Admitted to US Intensive Care Units for RSV Infection During the 2022 Seasonal Peak

Tuesday, August 15, 2023
Natasha Halasa
CONCLUSIONS AND RELEVANCE: In this cross-sectional study, most US infants who required intensive care for RSV LRTIs were young, healthy, and born at term. These findings highlight the need for RSV preventive interventions targeting all infants to reduce the burden of severe RSV illness.

Disposition and metabolomic effects of 2,2',5,5'-tetrachlorobiphenyl in female rats following intraperitoneal exposure

Saturday, August 12, 2023
Amanda Bullert
The disposition and toxicity of lower chlorinated PCBs (LC-PCBs) with less than five chlorine substituents have received little attention. This study characterizes the distribution and metabolomic effects of PCB 52, an LC-PCB found in indoor and outdoor air, three weeks after intraperitoneal exposure of female Sprague Dawley rats to 0, 1, 10, or 100 mg/kg BW. PCB 52 exposure did not affect overall body weight. Gas chromatography-tandem mass spectrometry (GC-MS/MS) analysis identified PCB 52 in...