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 ACB Seminar Series - Joy James promotional image

ACB Seminar Series - Joy James

Wednesday, October 14, 2026 9:30am to 10:30am
Bowen Science Building

Joy James, a Cell and Developmental Biology Graduate Student in Sam Stephen's Lab will present a seminar titled "Proinflammatory Cytokines Induce Golgi Remodeling In Pancreatic Β-cells Beyond Inos-no Signaling."

REDCap MyCap Training

Wednesday, October 14, 2026 10:00am to 11:00am
Virtual

This is the fifth step in the REDCap training series. In this training, we will discuss using the MyCap mobile app for data collection. We will cover features such as:

Creating participants

Creating tasks and schedules

Active tasks and their unique data output

Direct messages and announcements

This training is a demo and not hands-on. After this training, you will have a basic understanding of the MyCap mobile app for REDCap.

Register by clicking the virtual event link above or by going here:  https:/...

Molecular Physiology and Biophysics Workshop, Cobey Donelson promotional image

Molecular Physiology and Biophysics Workshop, Cobey Donelson

Wednesday, October 14, 2026 12:00pm to 1:00pm
Bowen Science Building

REDCap Data Handling

Thursday, October 15, 2026 10:00am to 11:00am
Virtual

This is the sixth and final step in the REDCap training series. In this training we won't use REDCap at all. Instead, we will cover ways to view and manage your exported REDCap data in Microsoft Excel and Sublime Text such as:

Populating data from one Excel sheet to another with vlookup()

Seeing specific data with column sorting and filtering

Ensuring data is cohesive by creating tables

Looking at how data relates to other data by creating pivot tables

Transforming unusable data to a usable format...

Degowin Blood Drive at Medical Center University

Thursday, October 15, 2026 10:00am to 3:00pm
General Hospital
The DeGowin Blood Center is hosting a blood drive from 10 a.m. to 3 p.m. on Thursday October 15th 2026 at the Fountain Lobby in the University Medical Center.
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Recent Articles from the University of Iowa

Monocyte-derived pro-angiogenic ocular macrophages identified by spatial transcriptomics are essential for choroidal neovascularization

Thursday, October 8, 2026
Andrew P Voigt
The human retina and underlying choroid have multiple well-organized vascular layers. However, retinal and choroidal neovascularization can develop in diseases such as diabetic retinopathy or neovascular age-related macular degeneration, which can result in destructive vision loss. Ocular macrophages are implicated in the pathogenesis of such neovascular diseases. To identify a potential pro-angiogenic macrophage subtype, we integrated 13 single-cell RNA sequencing datasets from human and mouse...

Bronchiectasis prevalence, incidence, and exacerbation rates among insured adults in the U.S.: a descriptive analysis

Tuesday, October 6, 2026
Cesar N Cristancho-Rojas
CONCLUSIONS: Observed prevalence-incidence widening gap suggests case accumulation over time and survival among continuously enrolled beneficiaries. Exacerbation burden was concentrated among individuals with prior exacerbations, chronic airway infection, and respiratory comorbidity, while exacerbation rates decreased over time across payers and subgroups, in part reflecting changes in cohort composition.

Dicer-independent miR-451a is upregulated in periodontitis and potentiates inflammation by impairing macrophage polarization and SOCS activity

Tuesday, October 6, 2026
Raza Ali Naqvi
CONCLUSION: miR-451a is a pathogen-responsive, PD-associated miRNA that promotes pro-inflammatory macrophage polarization, impairs bacterialphagocytosis, and amplifies inflammation through suppression of SOCS-mediated immune regulation. These findings identify the miR-451a-SOCS3/SOCS5 axis as a potential mechanism linking bacterial challenge to dysregulated macrophage responses in PD.

Efficient host transmission of measles virus: disentangling misconceptions from established findings

Monday, October 5, 2026
Angela Liu
SUMMARYMeasles virus (MeV) is considered the most contagious human virus. This review critically examines explanations for MeV's extraordinary transmissibility. Although substantial progress has been made in understanding MeV infection, pathogenesis, and host spread, the fundamental question of why MeV is markedly more transmissible than other structurally similar respiratory viruses within the same taxonomic families remains unresolved. Many commonly cited explanations are either incorrect,...

Denecimig (Mim8) prophylaxis over 52 weeks in adolescents and adults with hemophilia A: FRONTIER2 extension study

Friday, October 2, 2026
Victor Jiménez-Yuste
CONCLUSIONS: Denecimig maintained low ABRs over 52 weeks, was well tolerated, and improved patient-reported outcomes in adolescents and adults with HA with or without inhibitors.

Loss of CsrA in <em>Acinetobacter baumannii</em> leads to lethal dysregulation of alanine metabolism

Tuesday, September 29, 2026
Rosa L Sava
Posttranscriptional regulation is a key mechanism by which bacteria coordinate gene expression in response to changing environments. In the human pathogen Acinetobacter baumannii, the importance of posttranscriptional gene expression control is exemplified by CsrA, a highly conserved posttranscriptional regulator that is essential for viability in multiple settings, ranging from growth in rich laboratory media to infection-relevant conditions like human serum. However, csrA is dispensable for...

IRE1alpha Is Associated with Host Lipid Biosynthesis During Human Coronavirus OC43 Infection

Saturday, September 26, 2026
Kaitlin N James
Research into the replication of human coronaviruses has surged, but much remains unknown regarding the host factors that influence disease. These viruses often activate cellular endoplasmic reticulum (ER) stress responses, benefiting from incompletely understood downstream effects. In this study, we investigated the role of the host ER stress response component, inositol-requiring enzyme 1 α (IRE1α), in regulating lipid metabolism during human coronavirus OC43 (HCoV-OC43) infection. We found...

Impaired regulatory T-cell-mediated immune tolerance promotes neurodegeneration in glaucoma

Thursday, September 24, 2026
Huilan Zeng
Neurodegenerative diseases are increasingly recognized to involve detrimental interactions between the immune and nervous systems, yet whether failure of peripheral immune tolerance actively drives neuronal loss frequently remains unclear. Here, using primary open-angle glaucoma as a model of chronic neurodegeneration, we demonstrate that dysregulated adaptive immunity is sufficient to promote retinal ganglion cell degeneration. Peripheral blood mononuclear cells from glaucoma patients, but not...

The Virtual Eye: An Integrative Multiscale Framework for Mechanistic Modelling of Ocular Physiology and Disease

Monday, September 21, 2026
P J Luthert
The Virtual Eye initiative described here seeks to build a versatile and integrative in silico platform, 'The Virtual Eye' that can capture and simulate the biology, physiology and function of the human eye, from molecular interactions to organ-level behaviour, in both healthy and diseased states. This effort has the potential to substantially deepen our understanding of the visual process, clarify the mechanistic basis of ocular diseases across multiple spatial and temporal scales, and support...

A Zur-dependent regulatory RNA involved in maintaining zinc homeostasis in Staphylococcus aureus

Friday, September 18, 2026
Mathilde Charbonnier
Small regulatory RNAs (sRNAs) are key drivers of bacterial adaptation to environmental fluctuations, including iron and manganese restriction imposed by the host. This study explored the repertoire of sRNAs produced by the human pathogen Staphylococcus aureus in response to metal limitation. Two sRNAs were identified, S1077 and ZinS, that were regulated by zinc (Zn) availability. Further investigations revealed that, similar to the cnt operon from which it derives, S1077 synthesis is controlled...