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Carver College of Medicine Events

Pain Research Program Presentation - Agatha Greenway and Barbara Van Gorp, MPT, DPT, OCS, CSCS

Wednesday, November 20, 2024 9:00am to 10:00am
Carver Biomedical Research Building
The potential role of the central circuits in female specific light aversion" Presented by Agatha Greenway Graduate student in Dr. Levi Sowers's lab "PT private practice healthcare systems experience in a pragmatic clinical trial – expanding the research field" Presented by Barbara Van Gorp, MPT, DPT, OCS, CSCS Clinical Specialist Physical Therapist Rehabilitation Therapies University of Iowa Hospitals and Clinics
ACB Seminar Series - Emanuela Bruscia  promotional image

ACB Seminar Series - Emanuela Bruscia

Wednesday, November 20, 2024 9:30am to 10:30am
Bowen Science Building
Dr. Emanuela Bruscia, an Associate Professor of Pediatrics from the Yale School of Medicine will present a seminar titled "Pathological Lung Inflammation in Cystic Fibrosis: Insights into Macrophage-Driven Mechanisms."

REDCap MyCap Training

Wednesday, November 20, 2024 10:00am to 11:00am
Virtual
This is the fifth step in the REDCap training series. In this training, we will discuss using the MyCap mobile app for data collection. We will cover features such as: • Creating participants • Creating tasks and schedules • Active tasks and their unique data output • Direct messages and announcements • And more This training is a demo and not hands-on. After this training, you will have a basic understanding of the MyCap mobile app for REDCap. Register by clicking the virtual event link...
Hardin Open Workshops - Finding the Right Journal for your Manuscript (Zoom) promotional image

Hardin Open Workshops - Finding the Right Journal for your Manuscript (Zoom)

Wednesday, November 20, 2024 12:00pm to 1:00pm
Hardin Library for Health Sciences
There are an overwhelming number of health sciences journals, but how do you know which ones are best to target for submitting your work? This session will provide a demonstration of tools to use to create a list of appropriate journals to consider. Resources to help you evaluate the quality of health sciences journals will be reviewed. Time for guided practice using the resources will also be provided.   PLEASE NOTE Advance registration is required for Zoom classes, though walk-ins are...
The Upstream Approach to Healthcare Lecture Series Presents Jonathan Platt promotional image

The Upstream Approach to Healthcare Lecture Series Presents Jonathan Platt

Wednesday, November 20, 2024 12:00pm to 1:00pm
Virtual
The date and time for this lecture are Wednesday, Nov. 20, from noon to 1 p.m. This lecture will be offered both in person and over Zoom. If you attend in person, please go to room B111 in the Medical Laboratories. Food and drinks be provided! If you would like to attend in person, please sign up at the link provided: https://www.signupgenius.com/go/10C0C4AADAF2AA2FCC16-52448065-theupstream If you would like to attend virtually, please register via the Zoom link: https://uiowa.zoom.us/meeting...
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Recent Articles from the University of Iowa

High-grade B-cell lymphoma not otherwise specified, with diffuse large B-cell lymphoma gene expression signatures: Genomic analysis and potential therapeutics

Saturday, November 16, 2024
Waseem Lone
High-grade B-cell lymphoma not otherwise specified (HGBCL, NOS) has overlapping morphological and genetic features with diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL), leading to uncertainty in its diagnosis and clinical management. Using functional genomic approaches, we previously characterized HGBCL and NOS, that demonstrate gene expression profiling (GEP), and genetic signatures similar to BL. Herein, we characterize distinct HGBCL, NOS, cohort (n = 55) in adults (n = 45)...

Design, creation, and use of the Test Us Bank (TUB) COVID-19 sample biorepository

Monday, November 11, 2024
John Broach
Shortly after the first case of SARS-CoV-2 was diagnosed a public health emergency (PHE) was declared and a multi-agency response was initiated within the US federal government to create and propagate testing capacity. As part of this response, an unprecedented program designated Rapid Acceleration of Diagnostics (RADx) Tech was established by the National Institutes of Health (NIH) to facilitate the development of point-of-care tests for the COVID-19. The RADx Tech Clinical Studies Core (CSC),...

High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene

Tuesday, November 5, 2024
Fedik Rahimov
In Finland, the frequency of isolated cleft palate (CP) is higher than that of isolated cleft lip with or without cleft palate (CL/P). This trend contrasts to that in other European countries but its genetic underpinnings are unknown. We conducted a genome-wide association study in the Finnish population and identified rs570516915, a single nucleotide polymorphism highly enriched in Finns, as strongly associated with CP (P = 5.25 × 10^(-34), OR = 8.65, 95% CI 6.11-12.25), but not with CL/P (P =...

Exploratory Randomised Trial of Tranexamic Acid to Decrease Postoperative Delirium in Adults Undergoing Lumbar Fusion: A trial stopped early

Friday, November 1, 2024
Bradley J Hindman
CONCLUSIONS: A potential 33% relative decrease in postoperative delirium incidence justifies an adequately powered clinical trial to determine if intraoperative TXA decreases delirium in adults undergoing lumbar fusion.

Development of Worksheets for Immunomodulator Shared Decision-Making to Facilitate Patient-Clinician Communication: A Quality Improvement Project Employing Design Thinking Principles

Wednesday, October 30, 2024
Bharat Kumar
CONCLUSION: The WISDM template contains 7 elements that support SDM. Forty-five WISDMs were created for 23 immunomodulators. Further investigation will focus on how WISDMs exactly impact SDM.

Muscle inflammation is regulated by NF-κB from multiple cells to control distinct states of wasting in cancer cachexia

Wednesday, October 30, 2024
Benjamin R Pryce
Although cancer cachexia is classically characterized as a systemic inflammatory disorder, emerging evidence indicates that weight loss also associates with local tissue inflammation. We queried the regulation of this inflammation and its causality to cachexia by exploring skeletal muscle, whose atrophy strongly associates with poor outcomes. Using multiple mouse models and patient samples, we show that cachectic muscle is marked by enhanced innate immunity. Nuclear factor κB (NF-κB) activity in...

Inflammation impacts androgen receptor signaling in basal prostate stem cells through interleukin 1 receptor antagonist

Friday, October 25, 2024
Paula O Cooper
Chronic prostate inflammation in patients with benign prostate hyperplasia (BPH) correlates with the severity of symptoms. How inflammation contributes to prostate enlargement and/or BPH symptoms and the underlying mechanisms remain unclear. In this study, we utilize a unique transgenic mouse model that mimics chronic non-bacterial prostatitis in men and investigate the impact of inflammation on androgen receptor (AR) in basal prostate stem cells (bPSC) and their differentiation in vivo. We find...

Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments

Tuesday, October 22, 2024
Tong Wang
Since dietary intake is challenging to directly measure in large-scale cohort studies, we often rely on self-reported instruments (e.g., food frequency questionnaires, 24-hour recalls, and diet records) developed in nutritional epidemiology. Those self-reported instruments are prone to measurement errors, which can lead to inaccuracies in the calculation of nutrient profiles. Currently, few computational methods exist to address this problem. In the present study, we introduce a deep-learning...

Dynamic changes in macrophage polarization during the resolution phase of periodontal disease

Tuesday, October 22, 2024
Juhi R Uttamani
CONCLUSION: Resolution of periodontal inflammation is associated with M1 to M2 Mφ polarization after nonsurgical periodontal therapy. Assessment of Mφ markers can provide relevant clinical information on the successful response of periodontal therapy and may be used to target nonresponders.

A comprehensive review of sensors of radiation-induced damage, radiation-induced proximal events, and cell death

Saturday, October 19, 2024
Saurabh Saini
Radiation, a universal component of Earth's environment, is categorized into non-ionizing and ionizing forms. While non-ionizing radiation is relatively harmless, ionizing radiation possesses sufficient energy to ionize atoms and disrupt DNA, leading to cell damage, mutation, cancer, and cell death. The extensive use of radionuclides and ionizing radiation in nuclear technology and medical applications has sparked global concern for their capacity to cause acute and chronic illnesses. Ionizing...