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College of Pharmacy PSET Seminar Series: Filiz Korkmaz, PhD promotional image

College of Pharmacy PSET Seminar Series: Filiz Korkmaz, PhD

Tuesday, February 3, 2026 11:30am
College of Pharmacy Building

The Department of Pharmaceutical Sciences and Experimental Therapeutics (PSET) in the College of Pharmacy will host a seminar presented by: 

Filiz Korkmaz, PhD
Assistant Professor
Department of Microbiology and Immunology
University of Iowa

All are welcome to attend. No pre-registration required.

BMB Research Workshop promotional image

BMB Research Workshop

Tuesday, February 3, 2026 12:30pm to 1:20pm
Medical Education Research Facility

The Department of Biochemistry and Molecular Biology holds research workshops featuring internal speakers on Tuesdays, 12:30-1:20pm. For Spring 2026, these will occur in 2117 MERF. Presentation titles are not publicly available due to the use of unpublished research. Individuals interested in attending workshops or being added to the email list should contact the office at biochem@uiowa.edu.

Jan. 20: open

Jan. 27: open

Feb. 3: open

Feb. 10: open

Feb. 17: Tyler Woodward, PhD Candidate, 4th Year...

ACB Seminar Series - Joy James & Dr. Emma Thornell promotional image

ACB Seminar Series - Joy James & Dr. Emma Thornell

Wednesday, February 4, 2026 9:30am to 10:30am
Bowen Science Building

Joy James, a Cell and Developmental Biology Student in the Stephens Lab, will present a seminar titled “Pro-inflammatory Cytokines Mediate Early Β-cell Dysfunction In Type 1 Diabetes."

Dr. Emma Thornell, a Research Assistant Professor in the Department of Internal Medicine, will present a seminar titled “Sustainable Science: Integrating Sustainability and Innovation in Biomedical Research."

Hardin Open Workshops - PubMed (Zoom) promotional image

Hardin Open Workshops - PubMed (Zoom)

Wednesday, February 4, 2026 10:00am to 11:00am
Virtual

This hands-on session will help you improve your searching through best practices for basic and advanced searching and show you features for saving or exporting citations. The session will also help you understand medical subject headings (MeSH) and how they improve your search as well as the benefits of a MyNCBI account.

PLEASE NOTE:

Enrollment in HOW is open to all University of Iowa affiliates and residents of the state of Iowa. Advance registration is required for Zoom classes, though walk-ins...

Internal Medicine Grand Rounds 2/5/2026

Thursday, February 5, 2026 12:00pm to 1:00pm
General Hospital

"Acute Myeloid Leukemia: Are We Still Afraid? From urgency-driven decisions to precision-based care" by Prajwal Dhakal, MBBS

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Recent Articles from the University of Iowa

A Quantitative Lung Mucin Score to Identify Chronic Bronchitis

Tuesday, January 27, 2026
Mehmet Kesimer
CONCLUSIONS: The MUCQ metric was superior in distinguishing patients with CB compared to a total mucin concentration. Trials are needed to ascertain the prospective use of MUCQ metrics in research and clinical settings for assessment, management, and tracking therapeutic responses in CB and potentially other muco-obstructive conditions. (Funded by the National Institutes of Health and others.).

Immortalization and characterization of Schwann cell lines derived from NF1-associated cutaneous neurofibromas

Wednesday, January 21, 2026
Hua Li
Neurofibromatosis type 1 (NF1) is an autosomal dominant condition in which patients are heterozygous for a disruptive pathogenic variant in the NF1 gene. The most characteristic feature of the condition NF1 is the neurofibroma, a benign, multi-cellular tumor which initiates when a cell of the Schwann cell lineage gains a somatic pathogenic variant of the other NF1 allele. Neurofibromas developing at nerve termini in the skin are termed "cutaneous" neurofibromas (cNFs), while those developing...

Effectiveness of biologics for reducing occlusive mucus plugs in patients with severe asthma: a systematic review

Tuesday, January 20, 2026
Helena Aegerter
Asthma is a heterogeneous disease characterized by chronic airway inflammation and reversible airflow obstruction. Particularly in severe asthma, airway mucus plugs can contribute to substantial and persistent airflow obstruction, despite inhaled corticosteroid and bronchodilator treatment. Consequently, it is important that clinicians assess and treat mucus plugs. Increased mucus production and airway eosinophilia caused by type 2 (T2) inflammation contributes to mucus plug formation and...

Aroclor 1254 inhibits anti-inflammatory macrophage polarization through an AhR-dependent mechanism

Friday, January 16, 2026
Riley M Behan-Bush
Macrophages are critical regulators of tissue homeostasis and inflammation. During the development of chronic inflammatory diseases, tissue-resident macrophages often shift from an anti-inflammatory (M2) to a pro-inflammatory (M1) phenotype. Understanding the factors that drive this polarization shift is essential for elucidating the mechanisms underlying diseases such as cancer, cardiovascular disease, and metabolic syndrome. Environmental toxicants, including polychlorinated biphenyls (PCBs),...

Metastatic Uveal Melanoma Surveillance: A Delphi Panel Consensus

Saturday, January 10, 2026
Juan Alban
CONCLUSIONS: This is the first study to provide consensus-based guidance incorporating GEP and PRAME status into surveillance recommendations for uveal melanoma, offering a standardized framework to guide clinical practice and future research.

Anti-IL-15 treatment reduces acute lentivirus inflammation and signaling in the brain

Saturday, January 10, 2026
Daniel R Ram
HIV-associated neurocognitive disorder (HAND) remains a significant complication in people living with HIV, with inflammation playing a central role in its pathogenesis. Understanding how the brain's immune network responds to lentiviral infection is therefore critical. We show that acute simian immunodeficiency virus (SIV) infection elicits a robust resident brain immune response in control animals, marked by enhanced microglial ramification. In contrast, animals pretreated with...

Combination antiviral and anti-inflammatory therapy mitigates persistent neurological deficits in mice post SARS-CoV-2 infection

Wednesday, January 7, 2026
Abhishek Kumar Verma
Post-acute sequelae of COVID-19 (PASC) encompasses persistent neurological disease, including olfactory and cognitive dysfunction. The basis for this dysfunction is poorly understood. Here, we report neurological dysfunction for at least 120 d postinfection in mice infected with a virulent nonneurotropic mouse-adapted SARS-CoV-2. Long after recovery from nasal infection, we observed diminished tyrosine hydroxylase expression in olfactory bulb glomeruli and in substantia nigra. Similar changes...

Genetic diversity of Collaborative Cross mice implicates FFAR3 as a target for ILC2 anti-inflammatory reprogramming

Saturday, January 3, 2026
Mark Rusznak
Pulmonary group 2 innate lymphoid cells (ILC2s) are key drivers of Type 2 inflammation in diseases like asthma, yet the molecular mechanisms regulating their function are incompletely understood. Using the genetically diverse Collaborative Cross (CC) mouse panel, we mapped a quantitative trait locus (QTL) that governs ILC2 prevalence in the lung after aeroallergen exposure. This QTL induces a large population of ILC2s in the lung that are resistant to activation and have diminished Type 2...

Interferons Inhibit Ebola Virus Infection of Human Keratinocytes

Wednesday, December 31, 2025
Jonah Elliff
Orthoebolavirus zairense is the species name for Zaire Ebola virus (EBOV) within Filoviridae. This group of viruses can cause severe disease in humans, characterized by hemorrhagic shock, coagulation abnormalities, and severe inflammation. While tissue macrophages are critical targets early during EBOV infection, other cell types support viral replication as disease progresses. At late stages of infection, infectious EBOV is found on the surface of the skin, which may be a critical source of...

Human macrophages release exosomes containing anti-inflammatory microRNAs after phagocytosis of Leishmania infantum

Friday, December 26, 2025
Cinthia L Hudachek
INTRODUCTION: The protozoan Leishmania infantum causes visceral leishmaniasis, a disease associated with suppressed systemic innate and adaptive immune responses. Mechanisms underlying the generalized immune suppression are incompletely understood. Exosomes are a subset of microvesicles released from eukaryotic cells, which contain proteins, lipids, and nucleic acids, including microRNAs (miRNAs). These small regulatory RNAs can simultaneously modify the expression of many genes and pathways. We...